Annotation Detail
Information
- Associated Genes
- KRAS
- Associated Variants
-
KRAS p.Gly13Val (p.G13V)
(
ENST00000256078.10,
ENST00000311936.8,
ENST00000556131.2,
ENST00000557334.6,
ENST00000685328.1,
ENST00000686969.1,
ENST00000688940.1,
ENST00000692768.1,
ENST00000693229.1 )
KRAS p.Gly13Ala (p.G13A) ( ENST00000557334.6, ENST00000256078.10, ENST00000688940.1, ENST00000311936.8, ENST00000686969.1, ENST00000685328.1, ENST00000693229.1, ENST00000692768.1, ENST00000556131.2 )
KRAS p.Gly13Asp (p.G13D) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000685328.1, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gly13Val (p.G13V) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1, ENST00000557334.6, ENST00000685328.1 )
KRAS p.Gly13Ala (p.G13A) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gly13Asp (p.G13D) ( ENST00000556131.2, ENST00000557334.6, ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- In this analysis, use of cetuximab was associated with longer overall and progression-free survival among patients with chemotherapy-refractory colorectal cancer with p.G13D-mutated tumors than with other KRAS-mutated tumors.
- Pubmed
- 20978259
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.16
- Year of publication
- 2010
Drugs