Annotation Detail

Information
Associated Genes
PCSK9
Associated Variants
PCSK9 MUTATION
PCSK9 MUTATION
Associated Disease
atherosclerosis
Source Database
DisGeNET
Description
Drugs which negate the action of PCSK9 can produce substantial reductions in atherogenic lipoprotein cholesterol-carrying particles and thereby hold the potential for further reducing events associated with atherosclerotic cardiovascular disease.
Pubmed
25911073
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0115300422808758
Drugs