Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
IL23R p.Arg381Gln (p.R381Q)
(
ENST00000697230.1,
ENST00000697164.1,
ENST00000697163.1,
ENST00000697154.1,
ENST00000425614.3,
ENST00000347310.10,
ENST00000697165.1 )
NC_000006.12:g.52186235G>A
IL17F p.His161Arg (p.H161R) ( ENST00000336123.5, ENST00000699946.1 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1 )
NC_000006.12:g.52186235G>A
IL17F p.His161Arg (p.H161R) ( ENST00000336123.5, ENST00000699946.1 ) - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- The present study aimed to determine the association between the polymorphic variants of the IL-17A (rs2275913), IL-17F (rs763780) and IL-23R (rs11209026) genes and RA susceptibility, progression and response to therapy with TNF-α inhibitors.
- Pubmed
- 25387578
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.425384405819212
- Year of publication
- 2014
Drugs