Annotation Detail

Information
Associated Genes
PCSK9
Associated Variants
SMARCA4 c.4425-5330G>T ( ENST00000344626.10, ENST00000429416.8, ENST00000444061.8, ENST00000541122.6, ENST00000589677.5, ENST00000590574.6, ENST00000642628.1, ENST00000642726.1, ENST00000643296.1, ENST00000643549.1, ENST00000644737.1, ENST00000645460.1, ENST00000646484.1, ENST00000646510.1, ENST00000646693.2, ENST00000647230.1, ENST00000711079.1 )
rs599839
NC_000001.11:g.55030366T>C
ADAMTS7 SNV
SMARCA4 c.4425-5330G>T ( ENST00000344626.10, ENST00000429416.8, ENST00000444061.8, ENST00000541122.6, ENST00000589677.5, ENST00000590574.6, ENST00000642628.1, ENST00000642726.1, ENST00000643296.1, ENST00000643549.1, ENST00000644737.1, ENST00000645460.1, ENST00000646484.1, ENST00000646510.1, ENST00000646693.2, ENST00000647230.1, ENST00000711079.1 )
rs599839
NC_000001.11:g.55030366T>C
ADAMTS7 SNV
Associated Disease
Vascular Diseases
Source Database
DisGeNET
Description
Single-nucleotide polymorphisms associated with plasma LDL-c and vascular risk in the general population (rs11206510 (PCSK9), rs1122608 (LDLR), rs579459 (ABO) and rs599839 (SORT1)) were genotyped in a prospective cohort study of 5482 patients with vascular disease.
Pubmed
24251769
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2013
Drugs