Annotation Detail

Information
Associated Genes
HLA-DQA2
Associated Variants
HLA-DQA2 MUTATION
HLA-DQA2 MUTATION
Associated Disease
asthma
Source Database
DisGeNET
Description
The cluster analysis of these DEGs showed that 4 genes, including human leukocyte antigen (HLA-DQA1), HLA-DRB4, integrin 3 (ITGB3) and killer cell lectin-like receptor subfamily F member 1 (KLRF1) were all significantly expressed in 3 groups, which were significantly enriched in asthma, T1D and intestinal immune network for IgA production pathway.
Pubmed
24838153
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00318135759484294
Drugs