Annotation Detail

Information
Associated Genes
HTRA1
Associated Variants
HTRA1 c.-625G>A ( ENST00000648167.1 )
HTRA1 c.-625G>A ( ENST00000648167.1 )
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
Moreover, recent reports have shown that the rs11200638, a single nucleotide polymorphism (SNP) in the promoter region of the HTRA1 gene, is strongly associated with an increased prevalence of age-related macular degeneration (AMD).
Pubmed
19798546
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.266913741835053
Year of publication
2010
Drugs