Annotation Detail
Information
- Associated Genes
- CDKAL1
- Associated Variants
-
TCF7L2 c.552+40609G>A
(
ENST00000629706.2,
ENST00000277945.12,
ENST00000369395.6,
ENST00000355717.9,
ENST00000545257.6,
ENST00000627217.3,
ENST00000704414.1,
ENST00000352065.10,
ENST00000369397.8,
ENST00000538897.5,
ENST00000355995.9,
ENST00000534894.5 )
TCF7L2 c.876-1026C>T ( ENST00000538897.5, ENST00000352065.10, ENST00000369397.8, ENST00000369389.7, ENST00000355995.9, ENST00000534894.5, ENST00000277945.12, ENST00000369395.6, ENST00000355717.9, ENST00000545257.6, ENST00000629706.2, ENST00000349937.8, ENST00000704420.1, ENST00000627217.3, ENST00000704414.1 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 )
TCF7L2 c.552+40609G>A ( ENST00000277945.12, ENST00000352065.10, ENST00000355717.9, ENST00000355995.9, ENST00000369395.6, ENST00000369397.8, ENST00000534894.5, ENST00000538897.5, ENST00000545257.6, ENST00000627217.3, ENST00000629706.2, ENST00000704414.1 )
TCF7L2 c.876-1026C>T ( ENST00000277945.12, ENST00000349937.8, ENST00000352065.10, ENST00000355717.9, ENST00000355995.9, ENST00000369389.7, ENST00000369395.6, ENST00000369397.8, ENST00000534894.5, ENST00000538897.5, ENST00000545257.6, ENST00000627217.3, ENST00000629706.2, ENST00000704414.1, ENST00000704420.1 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- Novel risk loci for type 2 diabetes, single nucleotide polymorphism (SNP) rs7756992 in cyclin-dependent kinase 5 (CDK5) regulatory subunit associated protein 1-like 1 (CDKAL1), rs290487 and rs11196218 in transcription factor 7-like 2 (TCF7L2), were recently identified.
- Pubmed
- 19718565
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.420629582278103
- Year of publication
- 2010
Drugs