Annotation Detail

Information
Associated Genes
CLU
Associated Variants
MTHFR p.Ala263Val (p.A263V) ( ENST00000376585.6, ENST00000376583.7, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
CR1 c.6575+903A>G ( ENST00000367053.6, ENST00000367051.6, ENST00000367052.6, ENST00000367049.9, ENST00000400960.7 )
CLU c.247-478A>G ( ENST00000316403.15, ENST00000405140.7, ENST00000523500.5 )
MTHFR p.Ala263Val (p.A263V) ( ENST00000376583.7, ENST00000376585.6, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
CR1 c.6575+903A>G ( ENST00000367049.9, ENST00000367051.6, ENST00000367052.6, ENST00000367053.6, ENST00000400960.7 )
CLU c.247-478A>G ( ENST00000316403.15, ENST00000405140.7, ENST00000523500.5 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
In this case-control study, we aimed to investigate whether single nucleotide polymorphisms in MTHFR (rs1801133), PICALM (3851719), CLU (rs11136000), and CR1 (rs6701713) are associated with AD.
Pubmed
25359311
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.286840024957947
Year of publication
2014
Drugs