Annotation Detail
Information
- Associated Genes
- CLU
- Associated Variants
-
CLU c.247-478A>G
(
ENST00000316403.15,
ENST00000405140.7,
ENST00000523500.5 )
CLU c.247-478A>G ( ENST00000316403.15, ENST00000405140.7, ENST00000523500.5 ) - Associated Disease
- Impaired cognition
- Source Database
- DisGeNET
- Description
- We examined the effect of the novel Alzheimer's disease (AD) risk variant rs11136000 single nucleotide polymorphism in the clusterin gene (CLU) on longitudinal changes in resting state regional cerebral blood flow (rCBF) during normal aging and investigated its influence on cognitive decline in presymptomatic stages of disease progression.
- Pubmed
- 22795969
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2013
Drugs