Annotation Detail

Information
Associated Genes
PTPN22
Associated Variants
PTPN22 MUTATION
PTPN22 MUTATION
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
A C-to-T single-nucleotide polymorphism (SNP) located at position 1858 of human protein tyrosine phosphatase PTPN22 complementary DNA carries the highest risk of rheumatoid arthritis (RA) among all non-HLA genetic variants.
Pubmed
26019128
Section of the abstract supporting the evidence
OBJECTIVE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,GWASCAT,LHGDN,UNIPROT
DisGENET score for the Gene Disease association
0.524345610778177
Drugs