Annotation Detail

Information
Associated Genes
PTPN22
Associated Variants
PTPN22 MUTATION
PTPN22 MUTATION
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
ORs for associations with different HLA-DRB1 alleles, PTPN22 genotypes and smoking were calculated separately for each cohort as well as in meta-analysis in RA subsets defined by the presence/absence of anti-CarP and anticyclic citrullinated peptide (anti-CCP) antibodies.
Pubmed
24812286
Section of the abstract supporting the evidence
METHODS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,GWASCAT,LHGDN,UNIPROT
DisGENET score for the Gene Disease association
0.524345610778177
Drugs