Annotation Detail

Information
Associated Genes
GALT
Associated Variants
GALT p.Ser135Trp (p.S135W) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Ser135Leu (p.S135L) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Ser135Trp (p.S135W) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Ser135Leu (p.S135L) ( ENST00000378842.8, ENST00000450095.6 )
Associated Disease
Classical galactosemia
Source Database
DisGeNET
Description
This mutation was common in black patients with galactosemia and homozygotes (S135L/S135L) had no GALT activity or protein in their erythrocytes or lymphoblasts.
Pubmed
11592823
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.375200744836497
Year of publication
2001
Drugs