Annotation Detail
Information
- Associated Genes
- ICAM1
- Associated Variants
-
ICAM1 MUTATION
ICAM1 MUTATION - Associated Disease
- arteriosclerosis
- Source Database
- DisGeNET
- Description
- We found that SAA (80μg/mL) induced 3.5- to 37.8-fold increases in the expression of targets known to play important roles in the initiation and progression of atherosclerosis (i.e., ICAM-1, MCP-1, MMP-9 and TF) via NF-κB regulation within one hour after exposure.
- Pubmed
- 24785395
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00678604680200758
Drugs