Annotation Detail
Information
- Associated Genes
- FTO
- Associated Variants
-
FTO c.46-30685T>G
(
ENST00000636218.1,
ENST00000636491.1,
ENST00000637001.1,
ENST00000637969.1,
ENST00000471389.6 )
FTO c.124-4485A>T ( ENST00000471389.6, ENST00000637001.1, ENST00000637969.1, ENST00000636218.1, ENST00000636491.1 )
FTO c.46-30685T>G ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
FTO c.124-4485A>T ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- SNPs at four loci, 1q32.1 (MDM4, P = 2.1 × 10(-12) and LGR6, P = 1.4 × 10(-8)), 2p24.1 (P = 4.6 × 10(-8)) and 16q12.2 (FTO, P = 4.0 × 10(-8)), were associated with ER-negative but not ER-positive breast cancer (P > 0.05).
- Pubmed
- 23535733
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.121900093104562
- Year of publication
- 2013
Drugs