Annotation Detail
Information
- Associated Genes
- TOX3
- Associated Variants
-
rs3112612
rs11075884
rs13387042
rs17663555
rs566164
NC_000006.12:g.151627231G>A
rs3112612
rs11075884
rs13387042
rs17663555
rs566164
NC_000006.12:g.151627231G>A - Associated Disease
- Breast Cancer, Familial
- Source Database
- DisGeNET
- Description
- Seven of the 19 markers were significant in a multivariate predictive model of familial breast cancer in AJ women, three novel SNPs [rs17663555(5q13.2), rs566164(6q21), and rs11075884(16q22.2)], the FGFR2 haplotype, and three previously published SNPs [rs13387042(2q35), rs2046210(ESR1), and rs3112612(TOX3)], yielding moderate predictive power with an area under the curve (AUC) of the ROC (receiver-operator characteristic curve) of 0.74.
- Pubmed
- 23354978
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2013
Drugs