Annotation Detail
Information
- Associated Genes
- PTPN11
- Associated Variants
-
PTPN11 c.15-12708A>G
(
ENST00000687906.1,
ENST00000351677.7,
ENST00000392597.5,
ENST00000688597.1,
ENST00000635625.1,
ENST00000639857.2,
ENST00000690210.1 )
rs12526453 ( ENST00000332995.12, ENST00000674595.1, ENST00000674637.1, ENST00000676159.1, ENST00000689548.1 )
PTPN11 c.15-12708A>G ( ENST00000351677.7, ENST00000392597.5, ENST00000635625.1, ENST00000639857.2, ENST00000687906.1, ENST00000688597.1, ENST00000690210.1 )
rs12526453 ( ENST00000332995.12, ENST00000674595.1, ENST00000674637.1, ENST00000676159.1, ENST00000689548.1 ) - Associated Disease
- coronary artery disease
- Source Database
- DisGeNET
- Description
- Further meta-analyses showed that the rs12526453 of PHACTR11 gene (OR = 1.14, p < 0.0001, random-effect method) and the rs11066301 of PTPN11 gene (OR = 1.15, p < 0.0001, fixed-effects method) were associated with CAD risk in multiple populations.
- Pubmed
- 25123136
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs