Annotation Detail

Information
Associated Genes
HECTD4
Associated Variants
HECTD4 c.8131+277C>T ( ENST00000550722.5, ENST00000682272.1, ENST00000377560.9 )
HECTD4 c.177+1973A>T ( ENST00000377560.9, ENST00000682272.1, ENST00000550722.5 )
HECTD4 c.8131+277C>T ( ENST00000377560.9, ENST00000550722.5, ENST00000682272.1 )
HECTD4 c.177+1973A>T ( ENST00000377560.9, ENST00000550722.5, ENST00000682272.1 )
Associated Disease
Squamous cell carcinoma of esophagus
Source Database
DisGeNET
Description
Recent genome-wide association study (GWAS) on esophageal squamous-cell carcinoma (ESCC) among Chinese population has identified two novel single nucleotide polymorphisms (SNPs) rs11066280 and rs2074356 on C12orf51 gene.
Pubmed
25661349
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs