Annotation Detail

Information
Associated Genes
AGT
Associated Variants
AGT MUTATION
AGT MUTATION
Associated Disease
aortic aneurysm
Source Database
DisGeNET
Description
Consistently, myeloid TM-deficient hyperlipidemic mice (ApoE(-/-)/LysMcre/TM(flox/flox)) were resistant to AAA formation induced by angiotensin II infusion, along with reduced macrophage infiltration, suppressed matrix metalloproteinase activities, and diminished oxidative stress.
Pubmed
26338301
Section of the abstract supporting the evidence
APPROACH AND RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.125428837441606
Drugs