Annotation Detail
Information
- Associated Genes
- AGT
- Associated Variants
-
AGT MUTATION
AGT MUTATION - Associated Disease
- aortic aneurysm
- Source Database
- DisGeNET
- Description
- In early atherosclerotic lesions, Rgs1 regulates macrophage accumulation and is required for the formation and rupture of Angiotensin II-induced aortic aneurysms, through effects on leukocyte retention.
- Pubmed
- 25782711
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.125428837441606
Drugs