Annotation Detail
Information
- Associated Genes
- AGT
- Associated Variants
-
AGT MUTATION
AGT MUTATION - Associated Disease
- aortic aneurysm
- Source Database
- DisGeNET
- Description
- Treatment with pharmacological Notch inhibitor (DAPT [N-(N-[3,5-difluorophenacetyl]-L-alanyl)-S-phenylglycine t-butyl ester]) at day 3 or 8 of angiotensin II infusion arrested the progression of AAA in Apoe(-/-) mice, as demonstrated by a decreased luminal diameter and aortic width.
- Pubmed
- 25349182
- Section of the abstract supporting the evidence
- METHODS AND RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.125428837441606
Drugs