Annotation Detail
Information
- Associated Genes
- AGT
- Associated Variants
-
AGT MUTATION
AGT MUTATION - Associated Disease
- aortic aneurysm
- Source Database
- DisGeNET
- Description
- These results demonstrate that ACE2 exerts a modulatory role in AngII-induced AAA formation, and that therapeutic stimulation of ACE2 could be a benefit to reduce AAA expansion and rupture in patients with an activated renin-angiotensin system.
- Pubmed
- 25301841
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 13
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.125428837441606
Drugs