Annotation Detail
Information
- Associated Genes
- POT1
- Associated Variants
-
POT1 c.1595-111A>G
(
ENST00000357628.8,
ENST00000393329.5,
ENST00000653241.1,
ENST00000654766.1,
ENST00000655761.1,
ENST00000664366.1,
ENST00000668382.1 )
POT1 c.1595-111A>G ( ENST00000357628.8, ENST00000393329.5, ENST00000653241.1, ENST00000654766.1, ENST00000655761.1, ENST00000664366.1, ENST00000668382.1 ) - Associated Disease
- Malignant neoplasm of lung
- Source Database
- DisGeNET
- Description
- When stratified by genotype, there was a suggestion of a dose-response relationship between tertiles of telomere length and risk of lung cancer among the POT1 rs10244817 common variant carriers (OR (95% CI)=1.33 (0.47-3.75), 3.30 (1.14-9.56), respectively) but not among variant genotype carriers (p(interaction)=0.05).
- Pubmed
- 19285750
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00527694770136467
- Year of publication
- 2009
Drugs