Annotation Detail
Information
- Associated Genes
- ADRB2
- Associated Variants
-
ADRB2 MUTATION
ADRB2 MUTATION - Associated Disease
- Anxiety Disorders
- Source Database
- DisGeNET
- Description
- This single-nucleotide polymorphism is associated with reduced expression of the gene for the β2-adrenergic receptor (ADRB2) in CD4(+) lymphocytes of subjects with asthma, and it affects brain connectivity of the amygdala and the insula (a biomarker of anxiety).
- Pubmed
- 25918834
- Section of the abstract supporting the evidence
- MEASUREMENTS AND MAIN RESULTS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs