Annotation Detail

Information
Associated Genes
JAK2
Associated Variants
JAK2 c.1641+779C>G ( ENST00000381652.4 )
JAK2 c.1864+404T>C ( ENST00000381652.4 )
JAK2 c.1641+779C>G ( ENST00000381652.4 )
JAK2 c.1864+404T>C ( ENST00000381652.4 )
Associated Disease
Primary myelofibrosis
Source Database
DisGeNET
Description
We then genotyped 138 MPN patients (33 PV, 96 ET, and 9 PMF) with known JAK2 mutational status and 107 controls for a novel SNP, in addition to two SNPs known to be part of the 46/1 haplotype (rs10974944 and rs12343867).
Pubmed
22251709
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.294051045438073
Year of publication
2012
Drugs