Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF MUTATION
BRAF MUTATION
Associated Disease
Anaplasia
Source Database
DisGeNET
Description
This review will cover several cellular signaling pathways and mechanisms, including RET/PTC, RAS, BRAF, Notch, p53, and histone deacetylase, which are identified to play roles in the transformation and dedifferentiation process, and therapies that target these pathways.
Pubmed
25260367
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs