Annotation Detail
Information
- Associated Genes
- CDKAL1
- Associated Variants
-
CDKAL1 c.371+11426A>C
(
ENST00000274695.8,
ENST00000378610.1 )
CDKAL1 c.371+11642G>C ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+11642G>T ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+11426A>C ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+11642G>C ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+11642G>T ( ENST00000274695.8, ENST00000378610.1 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 ) - Associated Disease
- Diabetes
- Source Database
- DisGeNET
- Description
- We showed association of the minor allele C of rs10946398 (Odds Ratio (OR) = 1.21, 95% CI = 1.04-1.4, P = 0.016), allele C of rs7754840 (OR = 1.18, 95% CI = 1.01-1.37, P = 0.038), and allele G of rs7756992 (OR = 1.21, 95% CI = 1.04-1.42, P = 0.017) with higher diabetes risk thereby replicating the predisposing role of CDKAL1 in etiology of T2D.
- Pubmed
- 21611789
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00352874433704394
- Year of publication
- 2011
Drugs