Annotation Detail
Information
- Associated Genes
- MC4R
- Associated Variants
-
FTO c.46-23525T>A
(
ENST00000636491.1,
ENST00000636218.1,
ENST00000471389.6,
ENST00000637969.1,
ENST00000637001.1 )
rs17782313
rs10938397
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs17782313
rs10938397 - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- The genetic risk score (GRS), based on three significant SNPs (FTO rs9939609, MC4R rs17782313, GNPDA2 rs10938397), showed a positive association with SBP (P=5.17 × 10(-4)) and risk of hypertension (OR=1.22, 95% CI 1.12-1.33, P=6.07 × 10(-6)).
- Pubmed
- 23588626
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00908706543215305
- Year of publication
- 2013
Drugs