Annotation Detail
Information
- Associated Genes
- GNPDA2
- Associated Variants
-
BDNF p.Val148Met (p.V148M)
(
ENST00000532997.5,
ENST00000395981.7,
ENST00000356660.9,
ENST00000314915.6,
ENST00000439476.6,
ENST00000530861.5,
ENST00000395983.7,
ENST00000395986.6,
ENST00000525950.5,
ENST00000533246.5,
ENST00000418212.5,
ENST00000525528.1,
ENST00000533131.5,
ENST00000395978.7,
ENST00000438929.5 )
NC_000012.12:g.49853685G>A
FTO c.45+31536G>A ( ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1, ENST00000471389.6 )
NPC1 p.His215Arg (p.H215R) ( ENST00000269228.10 )
rs17782313
rs10938397
BDNF p.Val148Met (p.V148M) ( ENST00000314915.6, ENST00000356660.9, ENST00000395978.7, ENST00000395981.7, ENST00000395983.7, ENST00000395986.6, ENST00000418212.5, ENST00000438929.5, ENST00000439476.6, ENST00000525528.1, ENST00000525950.5, ENST00000530861.5, ENST00000532997.5, ENST00000533131.5, ENST00000533246.5 )
NC_000012.12:g.49853685G>A
FTO c.45+31536G>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
NPC1 p.His215Arg (p.H215R) ( ENST00000269228.10 )
rs17782313
rs10938397 - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Among those previously identified SNPs, we selected six (rs7138803, rs1805081, rs6499640, rs17782313, rs6265, and rs10938397, in or near obesity-related genes FAIM2, NPC1, FTO, MC4R, BDNF, and GNPDA2, respectively) because of the relatively high minor allele frequencies in Chinese individuals and tested the associations of the SNPs with BMI and obesity in Chinese children.
- Pubmed
- 20843981
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.152942950698469
- Year of publication
- 2010
Drugs