Annotation Detail
Information
- Associated Genes
- PPARG
- Associated Variants
-
PPARG MUTATION
PPARG MUTATION - Associated Disease
- amyotrophic lateral sclerosis
- Source Database
- DisGeNET
- Description
- Taken together, our data provide evidence that modulating PPARγ activity, although not effective at improving lifespan, provides a molecular target for mitigating locomotor dysfunction in TDP-43 and FUS but not SOD1 models of ALS in Drosophila.
- Pubmed
- 25432537
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00399568321108385
Drugs