Annotation Detail
Information
- Associated Genes
- FAIM2
- Associated Variants
-
NC_000012.12:g.49853685G>A
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
NPC1 p.His215Arg (p.H215R) ( ENST00000269228.10 )
rs10938397
NC_000012.12:g.49853685G>A
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
NPC1 p.His215Arg (p.H215R) ( ENST00000269228.10 )
rs10938397 - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- Of the 11 SNPs, only FTO rs9939609 was significantly associated with systolic BP (SBP; P=0.034) and three SNPs were significantly associated with diastolic BP (DBP; GNPDA2 rs10938397: P=0.026; FAIM2 rs7138803: P=0.015; NPC1 rs1805081: P=0.031) after adjustment for age, sex and hypertension status.
- Pubmed
- 23588626
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2013
Drugs