Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
TP63 c.62+33817C>T
(
ENST00000264731.8,
ENST00000320472.9,
ENST00000392460.7,
ENST00000418709.6,
ENST00000440651.6 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
TP63 c.62+33817C>T ( ENST00000264731.8, ENST00000320472.9, ENST00000392460.7, ENST00000418709.6, ENST00000440651.6 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 ) - Associated Disease
- Adenocarcinoma of lung (disorder)
- Source Database
- DisGeNET
- Description
- The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31).
- Pubmed
- 20871597
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.126905598933846
- Year of publication
- 2010
Drugs