Annotation Detail

Information
Associated Genes
CTLA4
Associated Variants
rs1863800
CTLA4 p.Thr17Ala (p.T17A) ( ENST00000295854.10, ENST00000487393.1, ENST00000648405.2, ENST00000696049.1, ENST00000696479.1 )
CTLA4 p.Thr17Ser (p.T17S) ( ENST00000295854.10, ENST00000487393.1, ENST00000648405.2, ENST00000696049.1, ENST00000696479.1 )
CTLA4 c.*1148+236G>A
rs11571302
rs11571297
ICOS c.*1024C>T ( ENST00000316386.11, ENST00000435193.1 )
rs1863800
CTLA4 p.Thr17Ala (p.T17A) ( ENST00000295854.10, ENST00000487393.1, ENST00000648405.2, ENST00000696049.1, ENST00000696479.1 )
CTLA4 p.Thr17Ser (p.T17S) ( ENST00000295854.10, ENST00000487393.1, ENST00000648405.2, ENST00000696049.1, ENST00000696479.1 )
CTLA4 c.*1148+236G>A
rs11571302
rs11571297
ICOS c.*1024C>T ( ENST00000316386.11, ENST00000435193.1 )
Associated Disease
Generalized vitiligo
Source Database
DisGeNET
Description
Examination of five SNPs in the CTLA4 gene (rs1863800, rs231775, rs3087243, rs11571302, rs11571297, rs10932037) in the same 126 families yielded no evidence of allelic or genotypic association with either generalized vitiligo or the expanded autoimmune phenotype.
Pubmed
18200060
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2008
Drugs