Annotation Detail
Information
- Associated Genes
- KCNQ1
- Associated Variants
-
KCNQ1 c.1514+8160A>G
(
ENST00000646564.2,
ENST00000335475.6,
ENST00000713725.1,
ENST00000496887.7,
ENST00000155840.12 )
rs10930963
rs2943641
rs972283
KCNQ1 c.1514+8160A>G ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000646564.2, ENST00000713725.1 )
rs10930963
rs2943641
rs972283 - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- The meta-analysis revealed that rs2943641 in the IRS1 locus was significantly associated with type 2 diabetes, (P = 0.0034, OR = 1.15 95% confidence interval; 1.05-1.26) and 3 SNPs, rs10930963 in the MTNR1B locus, rs972283 in the KLF14 locus, and rs231362 in the KCNQ1 locus, had nominal association with type 2 diabetes in the present Japanese samples (P<0.05).
- Pubmed
- 22046406
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.335743628580658
- Year of publication
- 2011
Drugs