Annotation Detail
Information
- Associated Genes
- CYP27B1
- Associated Variants
-
NC_000012.12:g.57768302G>T
NC_000012.12:g.57768302G>T - Associated Disease
- Hepatitis C, Chronic
- Source Database
- DisGeNET
- Description
- Associations between a functionally relevant polymorphism in the gene encoding the vitamin D 1α-hydroxylase (CYP27B1-1260 rs10877012) and the response to treatment with pegylated interferon-α (PEG-IFN-α) and ribavirin were determined in 701 patients with chronic hepatitis C. In addition, associations between serum concentrations of 25-hydroxyvitamin D(3) (25[OH]D(3)) and treatment outcome were analysed.
- Pubmed
- 22808108
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2012
Drugs