Annotation Detail

Information
Associated Genes
IGF2R
Associated Variants
IGF2R MUTATION
IGF2R MUTATION
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
Together, these results highlight the potential contribution of IGF-II receptor to AD pathology not only by regulating expression/processing of APP but also by its role in cellular vulnerability.
Pubmed
25939386
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.125362824093149
Drugs