Annotation Detail
Information
- Associated Genes
- NTRK2
- Associated Variants
-
NTRK2 MUTATION
NTRK2 MUTATION - Associated Disease
- Alzheimer's disease
- Source Database
- DisGeNET
- Description
- These results clarified a role of GSK3β in BDNF-dependent TrkB endocytosis and the subsequent signaling, and provided a potential new strategy by inhibiting GSK3β-induced Dyn1 phosphorylation for AD treatment.
- Pubmed
- 25484286
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN,RGD
- DisGENET score for the Gene Disease association
- 0.0880012979438318
Drugs