Annotation Detail

Information
Associated Genes
NR1D2
Associated Variants
NC_000019.10:g.39252525T>G
rs10853728
CXCL10 SNV
NC_000019.10:g.39252525T>G
rs10853728
CXCL10 SNV
Associated Disease
hepatitis C
Source Database
DisGeNET
Description
Because the first three SNPs were in very strong linkage disequilibrium with one another (r2 = 0.94-0.96), rs8099917 and rs10853728 were selected for an analysis of their influence on the achievement of rapid virological response [RVR; seronegativity for hepatitis C virus (HCV) RNA in treatment week 4] and sustained virological response (SVR; seronegativity for HCV RNA throughout 24 weeks of posttreatment follow-up).
Pubmed
21254157
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2011
Drugs