Annotation Detail

Information
Associated Genes
ODC1
Associated Variants
ODC1 MUTATION
ODC1 MUTATION
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
Pharmacologic disruption of the arginine utilization pathway by an inhibitor of arginase and ornithine decarboxylase protected the mice from AD-like pathology and significantly decreased CD11c expression.
Pubmed
25878270
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs