Annotation Detail
Information
- Associated Genes
- ITM2B
- Associated Variants
-
ITM2B MUTATION
ITM2B MUTATION - Associated Disease
- Alzheimer's disease
- Source Database
- DisGeNET
- Description
- Here, we aimed to investigate the effects of recombinant BRI2 ectodomain (rBRI276-266) on Aβ aggregation and on important molecular pathways involved in early stages of AD, including the unfolded protein response (UPR), phosphorylation and truncation of tau, as well as apoptosis.
- Pubmed
- 25336154
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00462444334702929
Drugs