Annotation Detail
Information
- Associated Genes
- IGHV1-68
- Associated Variants
-
DENND1A c.303-7710C>T
(
ENST00000373618.1,
ENST00000373620.7,
ENST00000373624.6,
ENST00000394215.7 )
DENND1A c.132+4911A>C ( ENST00000373618.1, ENST00000373620.7, ENST00000373624.6, ENST00000394215.7 )
DENND1A c.303-7710C>T ( ENST00000373618.1, ENST00000373620.7, ENST00000373624.6, ENST00000394215.7 )
DENND1A c.132+4911A>C ( ENST00000373618.1, ENST00000373620.7, ENST00000373624.6, ENST00000394215.7 ) - Associated Disease
- Ovarian Diseases
- Source Database
- DisGeNET
- Description
- Two strongly correlated Han Chinese PCOS risk variants on chromosome 9q33.3, rs10986105[C], and rs10818854[A], were replicated in samples of European ancestry with odds ratio of 1.68 (P = 0.00033) and odds ratio of 1.53 (P = 0.0019), respectively.
- Pubmed
- 22547425
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2012
Drugs