Annotation Detail
Information
- Associated Genes
- CD34
- Associated Variants
-
CD34 MUTATION
CD34 MUTATION - Associated Disease
- Primary myelofibrosis
- Source Database
- DisGeNET
- Description
- Our data indicate that the MF splenic microenvironment is characterized by increased levels of intact, functional CXCL12, which contributes to the localization of MF CD34(+) cells to the spleen and the establishment of extramedullary hematopoiesis.
- Pubmed
- 25461253
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00923895517239445
Drugs