Annotation Detail

Information
Associated Genes
SLC30A8
Associated Variants
KCNQ1 c.1795-29246C>T ( ENST00000526095.2, ENST00000496887.7, ENST00000155840.12, ENST00000713725.1, ENST00000646564.2, ENST00000335475.6 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 )
SLC30A8 p.Arg325Trp (p.R325W) ( ENST00000427715.2, ENST00000456015.7, ENST00000519688.5, ENST00000521243.5 )
SLC30A8 c.*1018A>G ( ENST00000427715.2, ENST00000456015.7, ENST00000519688.5 )
rs10811661
KCNQ1 c.1795-29246C>T ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000526095.2, ENST00000646564.2, ENST00000713725.1 )
CDKAL1 c.371+30101A>G ( ENST00000274695.8, ENST00000378610.1 )
SLC30A8 p.Arg325Trp (p.R325W) ( ENST00000456015.7, ENST00000519688.5, ENST00000521243.5, ENST00000427715.2 )
SLC30A8 c.*1018A>G ( ENST00000427715.2, ENST00000456015.7, ENST00000519688.5 )
rs10811661
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
We found that CDKAL1 (rs7756992), SLC30A8 (rs13266634, rs2466293), CDKN2A/2B (rs10811661) and KCNQ1 (rs2237892) were associated with T2DM with odds ratio from 1.21 to 1.35.
Pubmed
21103332
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.339815256661862
Year of publication
2010
Drugs