Annotation Detail
Information
- Associated Genes
- MTHFR
- Associated Variants
-
DRD2 p.Pro319= (p.P319=)
(
ENST00000346454.7,
ENST00000362072.8,
ENST00000538967.5,
ENST00000542968.5,
ENST00000544518.5 )
DRD2 p.Ser311Cys (p.S311C) ( ENST00000538967.5, ENST00000346454.7, ENST00000362072.8, ENST00000542968.5, ENST00000544518.5 )
TPH1 c.803+221C>A ( ENST00000250018.6, ENST00000682019.1, ENST00000528338.2, ENST00000714230.1 )
rs1019385
MTHFR p.Ala263Val (p.A263V) ( ENST00000376585.6, ENST00000376583.7, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
DTNBP1 c.161+1715G>A ( ENST00000338950.9, ENST00000344537.10, ENST00000355917.7, ENST00000622898.4 )
DRD2 p.Pro319= (p.P319=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
DRD2 p.Ser311Cys (p.S311C) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
TPH1 c.803+221C>A ( ENST00000250018.6, ENST00000528338.2, ENST00000682019.1, ENST00000714230.1 )
rs1019385
MTHFR p.Ala263Val (p.A263V) ( ENST00000376583.7, ENST00000376585.6, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
DTNBP1 c.161+1715G>A ( ENST00000338950.9, ENST00000344537.10, ENST00000355917.7, ENST00000622898.4 ) - Associated Disease
- Drug habituation
- Source Database
- DisGeNET
- Description
- According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB).
- Pubmed
- 20421849
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2010
Drugs