Annotation Detail

Information
Associated Genes
IGF1
Associated Variants
IGF1 MUTATION
IGF1 MUTATION
Associated Disease
adenoma
Source Database
DisGeNET
Description
When compared to densely granulated tumors, sparsely granulated adenomas were associated with a younger age at presentation, higher preoperative IGF-1 levels, elevated MIB-1 index and pure GH immunostaining, but did not differ significantly in terms of extrasellar invasion or outcome.
Pubmed
25238988
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD
DisGENET score for the Gene Disease association
0.125895776315646
Drugs