Annotation Detail

Information
Associated Genes
IRGM
Associated Variants
STAT3 c.-2+11876T>C ( ENST00000389272.7, ENST00000679185.1, ENST00000678792.1, ENST00000678913.1, ENST00000679014.1, ENST00000678906.1, ENST00000677479.1, ENST00000677723.1, ENST00000588969.5, ENST00000678572.1, ENST00000715205.1, ENST00000678960.1, ENST00000678048.1, ENST00000264657.10, ENST00000679166.1, ENST00000678674.1, ENST00000678535.1, ENST00000404395.3, ENST00000677442.1, ENST00000585517.5, ENST00000678827.1, ENST00000678043.1, ENST00000677152.1, ENST00000677603.1, ENST00000678044.1, ENST00000678905.1, ENST00000677421.1, ENST00000677030.1 )
rs13361189
rs4958847
rs11747270
rs10758669
STAT3 c.-2+11876T>C ( ENST00000264657.10, ENST00000389272.7, ENST00000404395.3, ENST00000585517.5, ENST00000588969.5, ENST00000677030.1, ENST00000677152.1, ENST00000677421.1, ENST00000677442.1, ENST00000677479.1, ENST00000677603.1, ENST00000677723.1, ENST00000678043.1, ENST00000678044.1, ENST00000678048.1, ENST00000678535.1, ENST00000678572.1, ENST00000678674.1, ENST00000678792.1, ENST00000678827.1, ENST00000678905.1, ENST00000678906.1, ENST00000678913.1, ENST00000678960.1, ENST00000679014.1, ENST00000679166.1, ENST00000679185.1, ENST00000715205.1 )
rs13361189
rs4958847
rs11747270
rs10758669
Associated Disease
Inflammatory Bowel Diseases
Source Database
DisGeNET
Description
We analysed five variants (rs10758669 within JAK2, rs744166 within STAT3, rs4958847, rs11747270 and rs13361189 within IRGM) in adult German inflammatory bowel disease patients (CD, n = 464; ulcerative colitis (UC), n = 292) and matched healthy controls (n = 508).
Pubmed
22065112
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.132725430379372
Year of publication
2012
Drugs