Annotation Detail
Information
- Associated Genes
- CCL21
- Associated Variants
-
STAT4 c.274-28828C>G
(
ENST00000392320.7,
ENST00000413064.6,
ENST00000358470.8,
ENST00000432798.2,
ENST00000450994.2,
ENST00000714287.1 )
rs13017599
PLCL2 c.3004-11369A>G ( ENST00000432376.5, ENST00000615277.5 )
STAT4 c.274-28828C>G ( ENST00000358470.8, ENST00000392320.7, ENST00000413064.6, ENST00000432798.2, ENST00000450994.2, ENST00000714287.1 )
rs13017599
PLCL2 c.3019-11369A>G ( ENST00000432376.5, ENST00000615277.5 ) - Associated Disease
- Arthritis, Psoriatic
- Source Database
- DisGeNET
- Description
- Significant evidence for association with susceptibility to PsA was found toa SNP mapping to the REL (rs13017599, p(trend)=5.2×10(4)) gene, while nominal evidence for association (p(trend)<0.05) was found to seven other loci including PLCL2 (rs4535211, p=1.7×10(-3)); STAT4 (rs10181656, p=3.0×10(-3)) and the AFF3, CD28, CCL21, IL2 and KIF5A loci.
- Pubmed
- 22328738
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2012
Drugs