Annotation Detail

Information
Associated Genes
IGF1
Associated Variants
IGF1 MUTATION
IGF1 MUTATION
Associated Disease
acromegaly
Source Database
DisGeNET
Description
Doses of the GH receptor (GHR) antagonist pegvisomant (PEGV) that normalize insulin-like growth factor 1 (IGF1) levels vary widely among acromegaly patients.
Pubmed
26243033
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.13486328961596
Drugs