Annotation Detail

Information
Associated Genes
IGF1
Associated Variants
IGF1 MUTATION
IGF1 MUTATION
Associated Disease
acromegaly
Source Database
DisGeNET
Description
An uncontrolled hyperactive GH-IGF-1 axis may play a dominant role in the development of PTC rather than the BRAFV600E mutation in patients with acromegaly.
Pubmed
25329702
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.13486328961596
Drugs