Annotation Detail

Information
Associated Genes
APOE
Associated Variants
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
Cox-regression models were used to assess the relative risks of developing AD and dementia (DSM-III-R criteria) according to FTO genotypes (rs9939609), taking into account APOE, physical inactivity, BMI, diabetes, and cardiovascular disease (CVD).
Pubmed
21098976
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.243208915269089
Year of publication
2011
Drugs