Annotation Detail
Information
- Associated Genes
- HTR3B
- Associated Variants
-
HTR3B c.-105_-103delGAG
(
ENST00000260191.8 )
HTR3B c.-105_-103delGAG ( ENST00000260191.8 )
HTR3B p.Tyr129Ser (p.Y129S) ( ENST00000537778.5, ENST00000260191.8 )
HTR3A c.-42T>C ( ENST00000375498.6, ENST00000504030.7, ENST00000355556.6, ENST00000506841.6 )
HTR3B p.Tyr129Ser (p.Y129S) ( ENST00000260191.8, ENST00000537778.5 )
HTR3A c.-42T>C ( ENST00000355556.6, ENST00000375498.6, ENST00000504030.7, ENST00000506841.6 ) - Associated Disease
- Major affective disorder 7
- Source Database
- DisGeNET
- Description
- Three single nucleotide polymorphisms (SNPs) in the HTR3A and HTR3B genes (rs1062613, rs1176744 and rs3831455) have been associated with bipolar affective disorder (BPAD) in pilot studies, and all of them are of functional relevance.
- Pubmed
- 22832903
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2012
Drugs